A Minimally Invasive Technique for the Management of Physiologic Gingival Melanin Hyperpigmentation: A Case Series.

An attractive smile enhances an individual's self-confidence. The overall harmony of a smile can be attributed to the interplay of the teeth's shape, color, and position along with the gingival tissue. Gingival pigmentation is observed across all human races, exhibiting variations from one race to another. Typically, gingival hyperpigmentation results from the abnormal buildup of melanin in the gingival tissue, imparting a dark appearance on the gums. Various procedures, collectively known as gingival depigmentation, are employed to address gingival hyperpigmentation. While the initial outcomes of depigmentation procedures are often promising, one common issue associated with them is the potential for re-pigmentation. This article aims to evaluate the clinical effectiveness and patient-reported outcomes of intraepidermal (oral mesotherapy) vitamin C injection for nonsurgical management of physiologic gingival melanin hyperpigmentation.

Root coverage with the restoration of non-carious cervical lesions: A systematic review and meta-analysis.

The progression of non-carious cervical lesions (NCCLs) leads to gingival recession (GR), which is restored with restorative materials, using different periodontal plastic surgery procedures. There is no consensus on which technique is superior to others. Therefore, the present systematic review aimed to assess the effectiveness of root coverage (RC) procedures in the restored and unrestored NCCLs in terms of clinical and patient-centered outcomes.We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) while searching 5 databases in addition to the gray literature. The Medical Subject Headings (MeSH) terms and keywords in the title and abstract fields, as well as in headings, were used to search the existing literature for the relevant publications on the effectiveness of RC procedures with the restoration of NCCLs over the past 3 decades (January 1990-July 2021). After applying the inclusion and exclusion criteria, 13 articles were read in full and critically analyzed. The quality analysis was performed using the Cochrane RevMan software.A total of 222 potentially relevant titles and abstracts were found after the initial electronic and manual search, and after removing duplicates. Applying the inclusion and exclusion criteria yielded 23 publications that were further analyzed for relevance and applicability. Following critical analysis, 13 publications were used for validity assessment and data extraction.In the teeth with NCCLs and GR, the restoration of NCCLs does not affect the percentage RC. However, it significantly decreases dentin hypersensitivity, and the patients' perception of esthetics and satisfaction.

Clinical efficacy of Vestibular Incision Subperiosteal Tunnel Access (VISTA) for treatment of multiple gingival recession defects: a systematic review, meta-analysis and meta-regression.

OBJECTIVES: This study investigated the efficacy of Vestibular Incision Subperiosteal Tunnel Access (VISTA) compared to other methods for treating multiple adjacent gingival recessions (MAGRs) through a systematic review and meta-analysis. MATERIALS AND METHODS: A systematic literature search was performed through June 2023, to identify clinical trials investigating VISTA for root coverage on MAGRs. A meta-analysis with meta-regression model was employed on the primary outcomes of mean and complete root coverages (MRC, CRC), comparing VISTA with other techniques. Clinical efficacy of various graft materials was assessed. RESULTS: Fourteen studies were included, 8 of which met the criteria for quantitative assessment. The cumulative MRC (88.15% ± 20.79%) and CRC (67.85% ± 21.72%) of VISTA were significantly higher compared to the tunneling technique (SMD = 0.83 (95% CI [0.36, 1.30], p < 0.01). The baseline recession depth showed a negative correlation with CRC, whereas baseline keratinized gingiva width exhibited a positive correlation with this outcome. CONCLUSIONS: The VISTA technique, particularly with acellular dermal matrix (ADM) or connective tissue graft (CTG) materials, offers superior outcomes compared to the tunneling technique. The capacity of platelet-rich fibrin (PRF) to substitute for connective tissue graft (CTG) in VISTA-root coverage was noteworthy, provided there is adequate keratinized tissue width. CLINICAL RELEVANCE: VISTA in concert with acellular dermal matrix or CTG resulted in improved root coverage, surpassing the outcomes achieved through tunneling. PRF emerged as a viable alternative to CTG, when used in conjunction with VISTA, demonstrating comparable mean root coverage. This is particularly evident in situations where sufficient keratinized gingiva is available and when patient comfort is taken into consideration.

Pink Aesthetics: Gummy Smiles and Gingival Recession.

The ideal smile is one where there is harmony between the 'white' (tooth) and 'pink' (periodontal) aesthetics. The developments in the field of periodontology have enhanced aesthetic outcomes when managing excessive gingival exposure in a 'gummy' smile or excessive tooth exposure in gingival recession cases. This paper aims to outline the aetiology, classification, and management of both a 'gummy' smile and gingival recession, putting a spotlight on aesthetics.

Soft Tissue Grafting Procedures before Restorations in the Esthetic Zone: A Minimally Invasive Interdisciplinary Case Report.

An esthetically pleasing smile is a valuable aspect of physical appearance and plays a significant role in social interaction. Achieving the perfect balance between extraoral and intraoral tissues is essential for a harmonious and attractive smile. However, certain intraoral deficiencies, such as non-carious cervical lesions and gingival recession, can severely compromise the overall aesthetics, particularly in the anterior zone. Addressing such conditions requires careful planning and meticulous execution of both surgical and restorative procedures. This interdisciplinary clinical report presents a complex case of a patient with esthetic complaints related to asymmetric anterior gingival architecture and severely discolored and eroded maxillary anterior teeth. The patient was treated using a combination of minimally invasive ceramic veneers and plastic mucogingival surgery, resulting in a successful outcome. The report emphasizes the potential of this approach in achieving optimal esthetic results in challenging cases, highlighting the importance of an interdisciplinary team approach in achieving a harmonious balance between dental and soft tissue aesthetics.

Aesthetic evaluation of free gingival graft applied by partial de-epithelialization and free gingival graft applied by conventional method: a randomized controlled clinical study.

OBJECTIVE: The aim of this clinical study was to compare the partially de-epithelialized free gingival grafts (d-FGGs) with the conventional free gingival grafts (FGGs) aesthetically using photographic analysis and Visual Analogue Scale (VAS). MATERIALS AND METHODS: A total of 30 defects were treated in 15 patients with attached gingiva insufficiency. In the split-mouth study, d-FGGs were applied on one side (test group), while FGGs were applied on the contralateral side (control group). Results of clinical periodontal parameters were evaluated in 6-month follow-up, and aesthetic evaluation results were evaluated in 1-, 3-, and 6-month follow-ups. RESULTS: Among the periodontal clinical parameters examined, only the keratinized tissue (KT) width was found to be statistically significantly higher in the test group compared to the control group. In the photo analysis evaluation, the ΔE value at the 3rd month was statistically significantly higher in the test group. In VAS evaluation, there was no significant difference between the two groups in the time periods examined. CONCLUSION: Photo analysis is an objective, sensitive, reproducible, and safe method that can be used in dentistry and medicine by detecting the slightest changes and giving more detailed and superior results than visual evaluation. The d-FGG application could provide acceptable aesthetic results by providing an appearance compatible with the gingival contour and gingiva in the adjacent region in creating keratinized gingiva. CLINICAL RELEVANCE: While the free gingival graft has color differences with the recipient area, the deep-thelialized gingival graft has a compatible appearance with the recipient area. Partially, de-epithelialized free gingival graft is a method with acceptable aesthetic results. TRIAL REGISTRATION: U.S. National Institutes of Health Clinical Trials: NCT04970524.

Minimal invasiveness in gingival augmentation and root coverage procedures.

Minimally invasive surgical procedures aim at optimal wound healing, a reduction of postoperative morbidity and, thus, at increased patient satisfaction. The present article reviews the concept of minimal invasiveness in gingival augmentation and root coverage procedures, and critically discusses the influencing factors, technical and nontechnical ones, and relates them to the underlying biological mechanisms. Furthermore, the corresponding outcomes of the respective procedures are assessed and evaluated in relation to a possible impact of a minimized surgical invasiveness on the clinical, aesthetic, and patient-related results.

Physiological reaction of anxious patients taking sedative medications before and after periodontal surgery.

Background/purpose: Clinicians use sedatives for anxiety patients at times in daily practice, but the direct influence of the medication on the wound healing of periodontal tissues is unknown. The aim of this study was to analyze the influence of the short-term administration of diazepam to patients with dental anxiety undergoing free gingival graft (FGG) procedures. Materials and methods: A total of 51 FGG procedures in 39 patients were included. Twenty-six anxious patients medicated with 5 mg of diazepam from the night before surgery to 7 days after surgery served as the medication group, and the rest served as the control group. Direct examination, photographs and H2O2 were used to evaluate the healing of palatal wounds. Stress levels and sleep quality, and salivary melatonin levels were assessed. Results: On Day 14, complete epithelization of the wounds was noted in 48.39% of the patients in the medication group and 35.29% of the patients in the control group. Regardless of whether they receive medication or not, groups with complete epithelialization by Day 14 had higher levels of preoperative melatonin than those without, with a P value of 0.02. The postoperative melatonin in the medication group tended to present higher levels than the control group. Conclusion: Higher preoperative melatonin levels can accelerate wound healing. The short-term administration of the diazepam seemed to facilitate palatal wound healing by reducing stress and maintaining postoperative melatonin levels. This is the first time the relationships between sedatives, melatonin levels and palatal wound healing has been reported.

Splith mouth randomized control trial comparison of T-PRF and subepithelial connective tissue graft in the treatment of maxillar multiple gingival recessions.

AIM: The aim of this study is to compare the treatment efficacy of the bilateral multiple gingival recession areas with a titanium-platelet-rich-fibrin (T-PRF) and subepithelial connective tissue graft (SCTG) combined with a modified coronal advanced flap (MCAF) and the clinical results. METHOD: In the study, 118 maxillary bilateral multiple Miller I recessions were treated. Gingival index, plaque index, probing pocket depth, gingival thickness, recession height, recession width, keratinized gingival width and open root surface area were measured at baseline and at 6 months. Postoperative pain levels Visual Analog Scale, healing status, wound healing index evaluated with. The results of both groups pre and postoperative were compared. RESULTS: The initial recession height was 2.15 ± 1.0 mm in the T-PRF group; 2.04 ± 0.80 mm in the SCTG group. After 6 months, the mean root closure rate was 61.77%, 75.31% in T-PRF and SCTG group, respectively. Clinical attachment gain was achieved in both groups compared to baseline. When the results were compared, the gains achieved in the SCTG group were statistically significantly higher. It was determined that patient satisfaction was higher in T-PRF group and wound healing was faster. CONCLUSION: Considering the advantages of T-PRF such as providing effective results in the treatment of defects, patient satisfaction and rapid recovery; It can be applied as an alternative to SCTG. CLINICAL SIGNIFICANCE: T-PRF can be an alternative to SCTG in the treatment of gingival recessions.

Intérêt de la greffe épithélioconjonctive au cours du traitement orthodontique multiattaches: rapport de 3 cas / Interest of free gingival grafting during multi-attachment orthodontic treatment: a 3-case report

Introduction. La récession gingivale (RG) entraine une exposition de la racine et une hypersensibilité. L'étiologie est multifactorielle. Une incidence plus élevée pourrait être observée au niveau des dents avec des phénotypes parodontaux fins ou si des forces orthodontiques ont été appliquées pour déplacer les dents en dehors de leurs processus alvéolaires. La greffe épithélioconjonctive (GEC) est indiquée pour prévenir ou corriger la RG et améliorer l'esthétique. L'objectif de ce rapport de cas est de montrer l'intérêt de la GEC dans la prise en charge des RG en cours de traitement orthodontique multiattaches. Observation clinique et prise en charge. Trois patientes en cours de traitement orthodontique multiattaches depuis 2 ans ont été référées dans la clinique de parodontie de l'Institut d'Odontologie et de Stomatologie de l'Université Cheikh Anta Diop de Dakar, avec des RG de type 2 (RT2) de Cairo sur la 31 et la 41. Un diagnostic parodontal de gingivite induite par le biofilm a été posé pour la première patiente. Les deux autres patientes présentaient une parodontite localisée de stade II et de grade B. La prise en charge a consisté en une thérapeutique initiale suivie d'une réévaluation à 2 mois. L'indication de la GEC a été posée avec comme objectifs de créer une bande de gencive kératinisée avec un approfondissement du vestibule en regard de la 31 et de la 41 et d'obtenir un recouvrement radiculaire. Des résultats satisfaisants ont pu être obtenus. Conclusion. Les rapports entre parodontie et orthodontie Impliquent un diagnostic initial précis et une planification thérapeutique coordonnée des intervenants.

Introduction. Gingival recession (GR) leads to root exposure and hypersensitivity. The etiology is multifactorial. A higher incidence may be observed in teeth with fine periodontal phenotypes, or if orthodontic forces have been applied to move teeth out of their alveolar processes. Free gingival grafting (FGG) is indicated to prevent or correct GR and improve aesthetics. The aim of this case report is to demonstrate the value of ECG in the management of GR during multiattachment orthodontic treatment. Case description and management. Three patients undergoing multiattachment orthodontic treatment for 2 years were referred to the periodontics clinic of the of the Institut d'Odontologie et de Stomatologie at Cheikh Anta Diop University in Dakar, with Cairo type 2 GR (RT2) on 31 and 41. A periodontal diagnosis of biofilm -induced gingivitis was made for the first patient. The other two patients presented with localized stage II, grade B periodontitis. Management consisted of initial therapy followed by reassessment at 2 months. The indication for FGG was to create a band of keratinized gingiva with deepening of the vestibule opposite 31 and 41, and to achieve root coverage. Satis factory results were obtained. Conclusion. The relationship between periodontics and orthodontics requires accurate initial diagnosis and coordinated treatment planning. .

Research progress on the tunnel technique for root coverage / 口腔疾病防治

@#Gingival recessions (GRs) result in root hypersensitivity, root surface caries, and esthetic problems. Various root coverage surgeries are being developed for periodontal plastic therapy. The tunnel technique (TUN) is one of the most widely applied surgeries due to its features of being minimally invasive, practical, excellent outcomes and long-term stability; however, there are still some limitations of this technique. The history and evolution from the envelope flap to TUN, including its efficiency when compared with coronally advanced flaps with a connective tissue graft (CTG), are reviewed in this paper. The limitations of TUN are discussed in consideration of our clinical experience; for example, there is high technique sensitivity when TUN is applied in GR>5 mm because of the great difficulty in covering the grafts. The advantages of surgical access, including vertical incisions in the vestibule, “W” type and pinhole access, are discussed for different situations. Mattress sutures and sling sutures in a single tooth or multiple teeth are applied in TUN. The different types of grafts, such as CTG, platelet-rich plasma, articular dermal matrix and xenogeneic collagen matrix, are described. Mechanical, chemical and biological conditioning of the root surface are recommended during surgery. Protecting the surgical area and taking antibiotics postoperatively are also very important. Finally, the modifications when TUN is applied with other kinds of techniques are discussed, including lateral closed TUN, laterally positioned flaps, double papilla flaps and frenuloplasty. Minimally invasive, esthetic, long-term stability and simplified techniques are the development trends of TUN in the future.

Papillary Reconstruction using Hyaluronic Acid: A Review.

PURPOSE: The aim of this review is to analyse the use of hyaluronic acid injection in the interdental space to reconstruct the papilla in animal models and humans. MATERIALS AND METHODS: Electronic databases were searched up to May 2022, and additional hand searching was performed. The search strategy was implemented according to the PRISMA guidelines. The inclusion criteria were: studies written in English, studies using hyaluronic acid, in vivo studies, studies with a precise number of specimens, case series with ≥6 patients, and studies published after 2010. The risk of bias was assessed for each study that could be evaluated. RESULTS: A total of 19 articles were selected and reviewed in this review. Due to the great heterogeneity of the protocols and materials, comparison between studies was not possible. However, using this technique, the studies found statistically significant improvements in most cases. The filling percentages ranged from 19% to 100%. Regarding patient satisfaction, the few studies that evaluated this parameter found statistically significant results with most patients willing to repeat the experience. Regarding side effects, only two studies reported them. Moreover, the procedure does not seem to be very painful. CONCLUSION: The results suggest that hyaluronic acid injections seem to be effective in reconstructing papillary volume. However, to date, too few clinical trials with a high level of proof have been conducted on this technique. Future studies will have to work on the size of the sample, the concentration of the product, the number of injections and the injection method.

Comparative efficacy of coronally advanced flap with and without guided tissue regeneration in the management of gingival recession defects: A split-mouth trial.

Background: The gingival recession causes tooth sensitivity, poor esthetics, and tooth mobility in severe cases. Scientific documentation revealed effective root coverage (RC) and increased keratinized tissue heights acquired with the coronally advanced flap (CAF) for multiple recession defects. Objectives: This research evaluates and compares the efficacy of CAF procedures with and without Type I collagen bio-absorbable membrane in guided tissue regeneration (GTR) in the treatment of Miller's Class I and II gingival recession. Materials and Methods: A total of 30 sites from 15 patients were selected for the study after fulfilling the presurgical phase of treatment. The chosen sites were randomly allocated into Group A CAF and Group B (CAF + Resorbable GTR membrane). The clinical variables such as plaque index, gingival index, recession depth (RD), recession width (RW), width of keratinized gingiva (WKG), clinical attachment level (CAL), and surface area of the defect were recorded at the baseline and 6 months postoperatively. Results: Both therapies resulted in a notable gain in RC with a mean of 73.13% and 71.60%, respectively, but it was not statistically significant when compared between the groups. Both the RD and RW were significantly reduced from baseline to 6 months postoperatively. Although there was a gain in WKG and CAL in both experimental sites, no significant difference was observed between both the groups. Conclusion: Although there are several RC procedures, CAF furnishes a foreseeable, straightforward, and appropriate perspective for treating Miller's Class I and II recessions. Integrating this approach with placing a bio-absorbable membrane does not seem to improve the results following surgical treatment of such defects. However, both groups showed the potential advantage of achieving RC.

Résumé Contexte: La récession gingivale provoque une sensibilité dentaire, une mauvaise esthétique et une mobilité dentaire dans les cas graves. La documentation scientifique a révélé une couverture efficace de la racine (RC) et une augmentation de la hauteur du tissu kératinisé acquises avec le lambeau coronalement avancé (CAF) pour de multiples défauts de récession multiples. Objectifs: Cette recherche évalue et compare l'efficacité des procédures CAF avec et sans membrane bio-absorbable de collagène de type I dans la régénération tissulaire guidée (RTC). de collagène de type I dans la régénération tissulaire guidée (RTG) dans le traitement de la récession gingivale de classe I et II de Miller. Matériaux et Méthodes: Un total de 30 sites de 15 patients ont été sélectionnés pour l'étude après avoir rempli la phase pré-chirurgicale du traitement. Les sites choisis ont été répartis au hasard dans le groupe A (CAF) et le groupe B (CAF + membrane GTR résorbable). Les variables cliniques telles que l'indice de plaque, l'indice gingival, la profondeur de la récession (RD), la largeur de la récession (GTR) ont été évaluées. gingivale, la profondeur de la récession (RD), la largeur de la récession (RW), la largeur de la gencive kératinisée (WKG), le niveau d'attachement clinique (CAL) et la surface du défaut. ont été enregistrés au début de l'étude et 6 mois après l'opération. Résultats: Les deux thérapies ont entraîné un gain notable de RC avec une moyenne de 73,13 % et 71,60 % respectivement. 71,60 %, respectivement, mais la comparaison entre les groupes n'était pas statistiquement significative. La RD et la RW ont toutes deux été réduites de manière significative de la ligne de base à 6 mois après l'opération. Bien qu'il y ait eu un gain en WKG et CAL dans les deux sites expérimentaux, aucune différence significative n'a été observée entre les deux groupes. observée entre les deux groupes. Conclusion: Bien qu'il existe plusieurs procédures de RC, la CAF fournit une perspective prévisible, directe et appropriée pour traiter la classe de Miller perspective prévisible, simple et appropriée pour traiter les récessions de classe I et II de Miller. L'intégration de cette approche avec la mise en place d'une membrane bio-absorbable ne semble pas améliorer les résultats après le traitement chirurgical. semble pas améliorer les résultats après le traitement chirurgical de ces défauts. Cependant, les deux groupes ont montré l'avantage potentiel de réaliser une RC. Mots-clés: Lambeau avancé coronaire, récession gingivale, régénération tissulaire guidée, chirurgie plastique parodontale, membrane résorbable.

Diagnostic Mock-Up as a Surgical Reduction Guide for Crown Lengthening: Technique Description and Case Report.

Background and Objectives: The report describes a technique using a diagnostic mock-up as a crown-lengthening surgical guide to improve the gingival architecture. Materials and Methods: The patient's primary concern was improving her smile due to her "gummy smile" and short clinical crowns. After clinical evaluation, surgical crown lengthening accompanied by maxillary central full-coverage single-unit prostheses and lateral incisor veneers was recommended. The diagnostic mock-up was placed in the patient's maxillary anterior region and used as a soft tissue reduction guide for the gingivectomy. Once the planned gingival architecture was achieved, a flap was reflected to proceed with ostectomy in order to obtain an appropriate alveolar bone crest level using the overlay. After six months, all-ceramic crowns and porcelain veneers were provided as permanent restorations. Results: A diagnostic mock-up fabricated with a putty guide directly from the diagnostic wax-up can be an adequate surgical guide for crown-lengthening procedures. The diagnostic wax-up was used to fabricate the diagnostic mock-up. These results suggested that it can be used as a crown-lengthening surgical guide to modify the gingival architecture. Several advantages of the overlay used in the aesthetic complex case include: (1) providing a preview of potential restorative outcomes, (2) allowing for the appropriate positioning of gingival margins and the desired alveolar bone crest level for the crown-lengthening procedure, and (3) serving as a provisional restoration after surgery. Conclusions: The use of a diagnostic mock-up, which was based on a diagnostic wax-up, as the surgical guide resulted in successful crown lengthening and provisional restorations. Thus, a diagnostic overlay can be a viable option as a surgical guide for crown lengthening.

Minimally invasive tunneling of a de-epithelialized connective tissue graft to improve gingival phenotype of lingual recession defects: A case report.

BACKGROUND: This case report describes a minimally invasive technique to increase the functional resistance of mandibular anterior lingual recession defects to inflammation. There are only a few case reports that describe the soft tissue augmentation of lingual gingival recession, of which none describe a tunneling technique without coronal advancement of the flap to treat a long span of multiple recession defects. Soft tissue augmentation of lingual recession defects is challenging due to the proximity to the tongue, frenum, vital structures, pre-existing thin phenotype, and limited access during surgery. METHODS AND RESULTS: A 30-year-old male was referred for the treatment of gingival recession on the lingual surfaces of teeth #22-27, with a diagnosis of recession type 2 (RT2). Mucogingival surgery included the preparation of the recipient site with a tunneling protocol, where apical muscular attachment was left undisturbed to isolate the flap from the movement of the tongue during normal function. As the goal was to not coronally advance the tunneled flap, the interdental papillae were not elevated and left intact, further optimizing blood supply. A free gingival graft was harvested, de-epithelialized extra-orally, and the resulting connective tissue graft (CTG) was fed through the tunnel and stabilized with sling sutures. Partial root coverage was achieved ranging from 50% to 90% at 4 months, consistent with the initial diagnosis of RT2. There was also a visually appreciable increase in gingival thickness and in the vestibular depth. CONCLUSION: A de-epithelialized CTG via tunneling without disturbing the deeper muscular attachment is a conservative method to improve phenotype of lingual recession defects. KEY POINTS: Why is this case new information? There are only a few case reports that describe soft tissue augmentation of lingual recession defects, of which none describe a tunneling technique without coronal advancement of the flap to treat a long span of multiple recession defects. This case report introduces a minimally invasive technique to increase the functional resistance of mandibular anterior lingual recession defects to plaque and calculus. What are the keys to successful management of this case? Control of gingival inflammation before and after surgery, with regular maintenance visits and oral hygiene instructions. Precise tunneling, leaving deeper muscular attachment on the floor of the mouth undisturbed. Connective tissue graft of even thickness that is fibrous in quality. What are the primary limitations to success in this case? A shallow lingual vestibule will not allow the clinician to leave deeper muscular attachment apical to tunneling undisturbed.

Efficacy of biologics in root coverage and gingival augmentation therapy: An American Academy of Periodontology best evidence systematic review and network meta-analysis.

BACKGROUND: The aim of this systematic review was to assess the efficacy of three biologics, namely autologous blood-derived products (ABPs), enamel matrix derivatives (EMD) and recombinant human platelet-derived growth factor BB (rhPDGF-BB), in root coverage and gingival augmentation therapy. METHODS: The protocol of this PRISMA 2020-compliant systematic review was registered in PROSPERO (CRD42021285917). After study selection, data of interest were extracted. A network meta-analysis (NMA) was conducted to assess the effect of different surgical interventions on the main clinical outcomes of interest (i.e., mean root coverage [MRC%], complete root coverage [CRC%], keratinized tissue width [KTW], gingival thickness [GT] change, and recession depth [RD] reduction). RESULTS: A total of 48 trials reported in 55 articles were selected. All studies reported on the treatment of gingival recession defects for root coverage purposes. Forty-six treatment arms from 24 trials were included in the NMA. These arms consisted of treatment with coronally advanced flap (CAF) alone, EMD + CAF, platelet-rich fibrin (PRF) + CAF, and subepithelial connective tissue graft (SCTG) + CAF. Regarding MRC%, SCTG+CAF was associated with a significant higher estimate (13.41%, 95% CI [8.06-18.75], P <  0.01), while EMD+CAF (6.68%, 95% CI [-0.03 to 13.4], P = 0.061) and PRF+CAF (1.03%, 95% CI [-5.65 to 7.72], P = 0.71) failed to show statistically significant differences compared with CAF alone (control group) or with each other. Similarly, only SCTG+CAF led to a significantly higher CRC% (14.41%, 95% CI [4.21 to 24.61], P < 0.01), while treatment arms EMD + CAF (13.48%, 95% CI [-3.34 to 30.32], P = 0.11) and PRF+CAF (-0.91%, 95% CI [-15.38, 13.57], p = 0.81) did not show significant differences compared with CAF alone or with each other. Differences in the CI of PRF+CAF (symmetrical around a zero adjunctive effect) and EMD+CAF (non-symmetrical) suggest that EMD could have some additional value compared with PRF. Treatment with SCTG+CAF led to a statistically significant higher RD reduction (-0.39 mm, 95% CI [-0.55 to 0.22], P < 0.01), however EMD+CAF (-0.13 mm, 95% CI [-0.29 to 0.01], P = 0.08) and PRF+CAF (-0.06 mm, 95% CI [-0.23 to 0.09], P = 0.39) failed to show significant differences compared with CAF or with each other. While SCTG+CAF was associated with a statistically significant higher gain of KTW (0.71 mm, 95% CI [0.48 to 0.93], P < 0.01), EMD+CAF (0.24 mm, 95% CI [-0.02 to 0.51], P = 0.08) and PRF+CAF (0.08 mm, 95% CI [-0.23 to 0.41], P = 0.58) did not result into significant changes compared with CAF alone or with each other. Regarding the use of rhPDGF-BB+CAF, although available studies have reported equivalent results compared with SCTG+CAF, evidence is very limited. CONCLUSIONS: The use of ABPs, EMD, or rhPDGF-BB in conjunction with a CAF for root coverage purposes is safe and generally promotes significant improvements respective to baseline clinical parameters. However, the adjunctive use of ABPs and EMD does not provide substantial additional improvements in terms of clinical outcomes and patient-reported outcome measures to those achieved using CAF alone, when baseline KTW is >2 mm. Both PRF+CAF and EMD+CAF rendered inferior MRC%, CRC%, RD reduction, and KTW gain compared with SCTG+CAF, which should still be considered the gold-standard in root coverage therapy. Although some studies have reported equivalent results for rhPDGF-BB+CAF compared with the gold-standard intervention, limited evidence precludes formal comparisons with CAF or SCTG+CAF that could be extrapolated to guide clinical practice.

American Academy of Periodontology best evidence consensus statement on the use of biologics in clinical practice.

A biologic is a therapeutic agent with biological activity that is administered to achieve an enhanced regenerative or reparative effect. The use of biologics has progressively become a core component of contemporary periodontal practice. However, some questions remain about their safety, indications, and effectiveness in specific clinical scenarios. Given their availability for routine clinical use and the existing amount of related evidence, the goal of this American Academy of Periodontology (AAP) best evidence consensus (BEC) was to provide a state-of-the-art, evidence-based perspective on the therapeutic application of autologous blood-derived products (ABPs), enamel matrix derivative (EMD), recombinant human platelet-derived growth factor BB (rhPDGF-BB), and recombinant human bone morphogenetic protein 2 (rhBMP-2). A panel of experts with extensive knowledge on the science and clinical application of biologics was convened. Three systematic reviews covering the areas of periodontal plastic surgery, treatment of infrabony defects, and alveolar ridge preservation/reconstruction and implant site development were conducted a priori and provided the foundation for the deliberations. The expert panel debated the merits of published data and exchanged experiential information to formulate evidence-based consensus statements and recommendations for clinical practice and future research. Based on an analysis of the current evidence and expert opinion, the panel concluded that the appropriate use of biologics in periodontal practice is generally safe and provides added benefits to conventional treatment approaches. However, therapeutic benefits and risks range based on the specific biologics used as well as patient-related local and systemic factors. Given the limited evidence available for some indications (e.g., gingival augmentation therapy, alveolar ridge preservation/reconstruction, and implant site development), future clinical studies that can expand the knowledge base on the clinical use of biologics in periodontal practice are warranted.

Comparative Evaluation of Platelet-Rich Fibrin versus Connective Tissue Grafting in Treatment of Gingival Recession Using Pouch and Tunnel Technique: A Randomized Clinical Study.

Aims: The aim of the study was to compare the clinical efficacy of platelet-rich fibrin (PRF) and connective tissue grafting in the treatment of gingival recession (GR) using pouch and tunnel (P and T) technique. Materials and Methods: A total of 40 Class I or Class II GR defects in 17 patients were randomized treated with P and T with PRF (Group I, n = 20) and P and T with CTG (Group II, n = 20). The parameters measured were plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), horizontal gingival recession (HGR), vertical gingival recession (VGR), width of attached gingiva (WAG), width of keratinised gingiva (WKG), gingival thickness-mid buccal (GTMB), and gingival thickness interdental papilla (GTIP). Postsurgical discomfort level (PSDL), hypersensitivity score (HS), and patient esthetic score (PES) were recorded using visual analog scale (VAS). The PI, GI, PPD, CAL, HGR, VGR, WAG, WKG, GTMB, and GTIP were assessed at pretreatment (baseline) and 1-, 3-, and 6-month posttreatment. The PSDL, HS, and PES were assessed at baseline, day 10, 1, 3, and 6-month posttreatment. Results: P and T with PRF and CTG resulted in root coverage of 73.75% ± 7.80% and 70.83% ±8.26%, respectively. Patient response and acceptance for the surgical treatment modality showed less discomfort and better esthetics in Group I as compared to Group II. Conclusions: PRF treated sites were comparable to the gold standard CTG with better patient acceptance and a lesser invasive approach in terms of graft procurement.

Cirugía plástica periodontal. Aplicación de la técnica de colgajo semilunar / Periodontal plastic surgery. Application of the semilunar flap technique / Cirurgia plástica periodontal. Aplicação da técnica de retalho semilunar

RESUMEN Introducción: cada día es más frecuente observar la preocupación de los pacientes por la presencia de trastornos mucogingivales, y dentro de estos, uno de los más comunes es la recesión periodontal. Esta puede acompañarse de sensibilidad radicular, mayor prevalencia de caries y abrasiones cervicales. Presentación de caso: el caso que presentamos se trató de un paciente de 25 años de edad del sexo masculino que acudió a nuestra consulta preocupado por su estética y sensibilidad dental a los cambios térmicos. El mismo presentaba una recesión periodontal de 3 mm a nivel del 13. Discusión: decidimos darle solución al problema con la técnica de colgajo semilunar, cumpliéndose el objetivo del trabajo al quedar resueltos los problemas de estéticas y sensibilidad del paciente una vez cubierta la raíz y aumentado el ancho la encía insertada. Conclusiones: al examen clínico los resultados mostraron un recubrimiento radicular, aumento del grosor de encía insertada, disminución de sensibilidad dental y estética aceptada por el paciente.

ABSTRACT Introduction: every day it is more frequent to observe the concern of patients for the presence of mucogingival disorders, and within these, one of the most common is periodontal recession. This can be accompanied by root sensitivity, increased prevalence of caries and cervical abrasions. Case presentation: the case we presented was a 25-year-old male patient who came to our office concerned about his aesthetics and dental sensitivity to thermal changes. It presented a periodontal recession of 3 mm at the level of 13. Discussion: we decided to solve the problem with the semilunar flap technique, fulfilling the objective of the work by solving the problems of aesthetics and sensitivity of the patient once the root is covered and the width of the inserted gum is increased. Conclusions: on clinical examination the results showed a root coating, increase in the thickness of the inserted gum, decrease in dental sensitivity and aesthetics accepted by the patient.

RESUMO Introdução: a cada dia é mais frequente observar a preocupação dos pacientes com a presença de distúrbios mucogingival, e dentro destes, um dos mais comuns é a recessão periodontal. Isso pode ser acompanhado de sensibilidade radicular, aumento da prevalência de cárter e abrasões cervicais. Apresentação do caso: o caso que apresentamos foi um paciente do sexo masculino de 25 anos que veio ao nosso consultório preocupado com sua estética e sensibilidade dentária às mudanças térmicas. Apresentou uma recessão periodontal de 3 mm ao nível de 13. Discussão: decidimos resolver o problema com a técnica de retalho semilunar, cumprindo o objetivo do trabalho resolvendo os problemas da estética e sensibilidade do paciente uma vez que a raiz é coberta e a largura da gengiva inserida é aumentada. Conclusões: no exame clínico os resultados mostraram revestimento radicular, aumento da espessura da gengiva inserida, diminuição da sensibilidade dentária e estética aceita pelo paciente.

Patient and professional use of the root coverage esthetic score (RES) and how it relates to patient satisfaction following periodontal plastic surgery.

BACKGROUND: Following periodontal plastic surgery in the treatment of recession defects, previous studies have reported that patients rate the esthetic outcomes more favorable than dental professionals. The root coverage esthetic score has been developed and suggested to serve as a comprehensive assessment instrument as it addresses several esthetic outcomes following root coverage procedures. However, no study has yet reported on patient use of this instrument. In the present study clinical, esthetic and patient-reported outcomes following periodontal plastic surgery were assessed. The primary objective was to compare the esthetic/clinical outcome as judged by the patient and by one dentist by using the root coverage esthetic score. The secondary objective was to evaluate the correlation between patient-reported outcomes, root coverage esthetic score and clinical parameters following treatment of recession defects. MATERIALS AND METHODS: Subjects that had undergone periodontal plastic surgery were invited to score the treatment outcome according to the root coverage esthetic score, which subsequently also was professionally scored by a dentist. Thereafter, the subjects answered a questionnaire on patient satisfaction. All types of surgical root coverage procedures in canine or incisor teeth were included. RESULTS: A total of 34 subjects were included, presenting 46 treated recessions. No statistically significant different score was found comparing the root coverage esthetic score by the patient and the professional. The majority of subjects was satisfied with the treatment outcome, and most would have undergone the treatment again. CONCLUSION: The root coverage esthetic score assessment can be conducted by patients and was not statistically significant different to that of the professional. Patient satisfaction is not always dependent on complete root coverage or the other clinical parameters included in the root coverage esthetic score.